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Cyanide poisoning antidote mechanism
Cyanide poisoning antidote mechanism









cyanide poisoning antidote mechanism

When released in an enclosed area, cyanide can be particularly deadly and impact a victim very quickly. Symptoms of acute cyanide poisoning include headache, vertigo, lack of motor coordination, weak pulse, abnormal heartbeat, vomiting, stupor, convulsions, coma, and even death.

cyanide poisoning antidote mechanism

This means it rapidly shuts down many of the fundamental biochemical processes the body needs to survive. The antidote is also unique because it can be taken orally (current antidotes must be given intravenously) and may be administered up to an hour prior to cyanide exposure.Ĭyanide is a rapid acting toxin that inhibits cellular respiration - it prevents the body from using oxygen. Researchers hope to begin human clinical trials during the next three years. The antidote was tested on animals and has been exceptionally effective, Patterson said. Giving emergency responders more time is important because it's not likely that someone will be exposed to cyanide near a paramedic." "The antidote is also effective over a wider time window. "It's much, much faster than current antidotes," Patterson said. This antidote works in less than three minutes - meeting the United States Department of Defense "three minute solution" standard. Patterson is developing an antidote that was discovered by retired University of Minnesota Professor Herbert Nagasawa. Current cyanide antidotes work slowly and are ineffective when administered after a certain point, said Steven Patterson, Ph.D., principal investigator and associate director of the University of the Minnesota Center for Drug Design.











Cyanide poisoning antidote mechanism